王迪个人简历

发稿时间:2024-09-09浏览次数:10

王迪,博士,讲师

通讯地址:山东省济宁市太白湖新区荷花路133号  

电子邮箱:wangdi_42869@163.com


教育和工作经历

2024-2025    澳大利亚国立大学,医学研究,博士后

2020-2025    澳大利亚国立大学,医学研究,博士

2016-2017   美国西奈山医学院,免疫学,访问学者

2009-2019    解放军总医院第八医学中心,临床检验,主管技师

2006-2009    海军军医大学,生物化学与分子生物学,硕士

2002-2006    清华大学,电子信息工程,本科

研究领域与方向

1. RNA的结构与功能。

2.  结核菌巨噬细胞相互作用。

荣誉、奖励及主要社会兼职

排名第一获得2014年军队科技进步奖三等奖

主持科研基金项目

1.国家自然科学基金青年项目:lincRNA-cox2在结核菌感染中调节细胞自噬功能的研究(结题),2015.01 - 2017.12

2. 澳大利亚首都领地癌症协会基金:Harnessing RNA-Protein Interactions for the Regulation of Heptocellular Carcinoma Progression(在研),2025.05 - 2027.05

代表性论文

1.Wang D, Lu R, Yan F, Lin Y, Wang H, Xiong H. Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis. Journal of Translational Medicine. 2025;23(1):213. (第一作者,中科院二区)

2.Jiang Y, Zhang X, Wang B, Tang L, Liu X, Ding X, Dong Y, Lei H, Wang D*, Feng H. Single-cell transcriptomic analysis reveals a decrease in the frequency of macrophage-RGS1high subsets in patients with osteoarticular tuberculosis. Molecular Medicine. 2024;30(1):118. (通讯作者,中科院二区)

3.Wang D, Lin Y, Xu F, Zhang H, Zhu X, Liu Z, Hu Y, Dong G, Sun B, Yu Y, Ma G, Tang Z, Legarda D, Ting A, Liu Y, Hou J, Dong L, Xiong H*. SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis. EBioMedicine. 2022;85:104278. (第一作者,中科院一区)

4.Chen W, Liu Z, Zheng Y, Wei B, Shi J, Shao B, Wang D*. Selenium donor restricts the intracellular growth of Mycobacterium tuberculosis through the induction of c-Jun-mediated both canonical autophagy and LC3-associated phagocytosis of alveolar macrophages. Microbial Pathogenesis. 2021;161(Pt B):105269. (通讯作者,中科院三区)

5.Cruz LY, Wang D, Liu J. Biosynthesis of selenium nanoparticles, characterization and X-ray induced radiotherapy for the treatment of lung cancer with interstitial lung disease. Journal of Photochemistry and Photobiology B: Biology. 2019;191:123-127. (共同第一作者,中科院一区)

6.Wu Y, Ding X, Ding L, Zhang Y, Cui L, Sun L, Li W, Wang D, Zhao Y. Synthesis and antibacterial activity evaluation of novel biaryloxazolidinone analogues containing a hydrazone moiety as promising antibacterial agents. European Journal of Medicinal Chemistry. 2018;158:247-258. (通讯作者,中科院一区)

7.Liu Z, Zhou G, Deng X, Yu Q, Hu Y, Sun H, Wang Z, Cheng H, Jia CWang D. Analysis of miRNA expression profiling in human macrophages responding to Mycobacterium infection: Induction of the immune regulator miR-146a. Journal of Infection. 2014;68(6):553-561. (通讯作者,中科院一区)

8.Wang D, Zhao Y, Liu Z, Lei H, Dong M, Gong P. In vitro and intracellular activity of 4-substituted piperazinyl phenyl oxazolidinone analogues against Mycobacterium tuberculosis. Journal of Antimicrobial Chemotherapy. 2014 Jun;69(6):1711-4. (第一作者,中科院二区)

9.Liu Z#, Wang D#, Hu Y, Zhou G, Zhu C, Yu Q, Chi Y, Cao Y, Jia C, Zou Q. MicroRNA-146a negatively regulates PTGS2 expression induced by Helicobacter pylori in human gastric epithelial cells. Journal of Gastroenterology. 2013 Jan;48(1):86-92. (共同第一作者,中科院一区)

10.Wang D, Zhu X, Cui C, Jiang H, Li Z, Dong M, Zhu W, Wang JG. Discovery of novel acetohydroxyacid synthase inhibitors as in vitro active agents against Mycobacterium tuberculosis by virtual screening and bioassay. Journal of Chemical Information and Modeling. 2013;53(2):343-353. (第一作者,中科院二区)

11.Li P, Jiang Y, Liu Z, Liu XH, Wang G, Li ZMWang D. Synthesis and evaluation of novel monosubstituted Sulfonylurea Derivatives as Antituberculosis Agents. European Journal of Medicinal Chemistry. 2012;50:18-26. (通讯作者,中科院一区)

12.Wang D, Pan L, Cao G, Lei H, Meng X, He J, Dong M, Li Z, Liu Z. Evaluation of the in vitro and intracellular efficacy of new monosubstituted sulfonylureas against extensively drug-resistant tuberculosis. International Journal of Antimicrobial Agents. 2012;40(5):463-466. (第一作者,中科院一区)

13.Wang D, Wang F, Tan Y, Dong L, Chen L, Zhu W, Wang H. Discovery of potent small molecule inhibitors of DYRK1A by structure-based virtual screening and bioassay. Bioorganic & Medicinal Chemistry Letters. 2012;22(1):168-171. (第一作者,中科院二区)